Natural Bio Care’s Young Bones builds bone mass and tempers pain associated with osteoporosis, as shown
by the results of clinical trials conducted by renowned bone health expert Dr. Susan Brown and her team of
researchers with the Osteoporosis Education Project.
In the first U.S. research study of traditional Chinese herbs for osteoporosis reversal and anti-aging effects,
Dr. Brown spent more than six months engaged in a series of clinical trial testing to determine the efficacy
of the Young Bones formula.
Dr. Brown and her team have researched a number of natural approaches to bone health maintenance and
regeneration. Dr. Brown said no other product has proved as promising in preventing and treating
osteoporosis than Young Bones.
Dr. Brown’s series of groundbreaking studies, beginning in March 2003, enlisted postmenopausal women
who took 2 600-mg Young Bones pills twice a day for 12 weeks. All study subjects had excessive bone
loss and were suffering from one or another unwanted symptom of aging and/or osteoporosis.
Improvements in such symptoms occurred early in the study and were consistent and enduring, said Dr.
Brown. In nearly all cases, symptom improvement was dramatic and highly appreciated by study subjects.
As very positive and intriguing initial results were seen in the first study subjects, Dr. Brown expanded the
scope of research for the last two subjects to enter the study. This amplification and extension of the study
looked at markers of bone formation as well as bone breakdown and bone mineral density changes in the
last two study subjects. Further, as her preliminary data suggested that Young Bones caused an increase in
bone density, at the end of the original 12-week trial she further expanded the study. This new study
segment was designed to look at bone mineral density changes after six month’s use of the Young Bones
product. While still on-going, preliminary data from both extension studies indicate that the Young Bones
formula indeed enhances bone formation and leads to increases in bone mineral density.
Most notable was Young Bones’ capability to stimulate new bone formation. Dr. Brown was able to show
this because at six weeks into the study the vast majority of subjects had experienced an increase in bone
breakdown, which indirectly suggests an accompanying increase in bone formation.
In the initial pilot study, Dr. Brown attempted to measure the ways in which the Young Bones formula
alters the bone breakdown process. As people age there is a tendency to breakdown more bone than
formed. This is normal bone loss and need not create excessive bone loss and weakened bones. However, if
the gap between bone breakdown and bone build-up is excessive and prolonged then excessive bone
thinning and osteoporosis occur. Bone resorption (bone breakdown) can be assessed by the NTx urine
marker. Osteoporosis medications that halt bone loss do so by limiting bone
breakdown. But they do not enhance the bone build-up process. The results
of this pilot study suggest that Young Bones is able to stimulate bone repair and new bone growth through
mechanisms that involve enhancement of both bone breakdown and bone formation.
To test the impact of the Young Bones’ formula on bone formation, two of the last subjects to enter the
study were subject to expanded testing over a longer period of time. This testing included not only the
serum NTx, but also testing of the bone formation markers known as osteocalcin and bone alkaline
phosphatase. These bone formation markers were tested at baseline, six, 12 and 24 weeks. In addition, bone
mineral density was tested at baseline with a follow-up test at 24 weeks. Bone mineral density changes, of
course, are considered the definitive marker of bone formation.
All in all, the data from each segment of Dr. Brown’s on-going research suggests that Young Bones’
formula enhances bone formation and acts as an “adaptogen”. As an adapotgen, the action of the formula
can vary from individual to individual according to the person’s unique biochemistry. In some cases the
formula would initially stimulate more new bone formation than it would decrease bone breakdown. In
other cases the immediate action of the formula would be more to halt excessive bone breakdown then
foment bone formation.
In all cases, Dr. Brown expects that over time bone breakdown would be normalized and bone formation
encouraged with a net gain of bone. Such findings would corroborate the extensive studies of Young Bones
in Taiwan. Those studies reported gains in bone mineral density with only six months’ use of this 1,000-
year-old herbal formula.
When it came to symptoms suffered by the study’s subjects, those evaluated as most significant fell into
two general categories: (1) Pain, stiffness, and problems with mobility; (2) Menopause and aging-related
symptoms.
As early as a few weeks into the study most subjects noticed improvement in at least some of their
symptoms. By 12 weeks, the improvement in symptoms was striking for most study subjects. Below is a
summary overview of symptom changes by major category.
Pain and Movement Symptom Changes with 12 Weeks Use of Young Bones Formula:
• There was a 57% reduction in overall pain, stiffness and mobility problems;
• There was a 67% reduction in lower back pain in particular.
Menopause and Aging Related Symptoms With 12 Weeks Use of Young Bones:
• There was a 72% reduction in headaches
• There was a 47% reduction in insomnia problems
• There was a 36% reduction in fatigue
• There was a 35% reduction in dry skin and wrinkles
• There was a 33% reduction in mood swings
Additional benefits often reported included increased strength and growth of finger and toe nails. Hair
growth was mentioned occasionally.
